Relaxin's Potential Implications in Early Pregnancy in Mares

Simple item page
atmire.migration.oldid4439
dc.contributor.advisorKlein, Claudia
dc.contributor.advisorYates, Robin
dc.contributor.authorSchwinghamer, Rose Anna-Marie
dc.contributor.committeememberThundathil, Jacob
dc.contributor.committeememberKastelic, John
dc.contributor.committeememberChenier, Tracey
dc.date.accessioned2016-05-19T16:30:16Z
dc.date.available2016-05-19T16:30:16Z
dc.date.issued2016
dc.date.submitted2016en
dc.description.abstractRelaxin is expressed at high levels from the conceptus during the first 16 d of pregnancy in mares. The overall objective was to determine the potential implications of relaxin in equine endometrium, and the expression of RLN, RXFP1, RXFP2, RXFP3 and RXFP4 in pregnant and non-pregnant equine endometrium as well as in the conceptus. The location of RXFP1 in pregnant endometrium was examined and effects of relaxin on inhibition of PGF2α were detailed. The hypothesis that relaxin inhibits endometrial release of PGF2α and is the maternal recognition of pregnancy factor in mares was tested. This hypothesis was rejected with the conclusion that whereas relaxin is important in equine pregnancy, it is not the maternal recognition of pregnancy factor.en_US
dc.identifier.citationSchwinghamer, R. A. (2016). Relaxin's Potential Implications in Early Pregnancy in Mares (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/27611en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/27611
dc.identifier.urihttp://hdl.handle.net/11023/3026
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.facultyVeterinary Medicine
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectVeterinary Science
dc.subject.classificationRelaxinen_US
dc.subject.classificationMaternal Recognition of Pregnancyen_US
dc.subject.classificationEquineen_US
dc.subject.classificationProstaglandin F2αen_US
dc.subject.classificationProgesteroneen_US
dc.subject.classificationConceptusen_US
dc.subject.classificationMareen_US
dc.subject.classificationPregnancyen_US
dc.titleRelaxin's Potential Implications in Early Pregnancy in Mares
dc.typemaster thesis
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
Files
Collections
Open Theses and Dissertations