Cartilage and chondrocyte response to extreme muscular loading and impact loading: Can in vivo pre-load decrease impact-induced cell death?

Date
2015-07
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Impact loading causes cartilage damage and cell death. Pre-loading prior to impact loading may protect cartilage and chondrocytes. However, there is no systematic evidence and understanding of the effects of pre-load strategies on cartilage damage and chondrocyte death. This study aimed at determining the effects of the pre-load history on impact-induced chondrocyte death in an intact joint.
Description
Keywords
chondrocyte, chondrocyte death, joint contact pressure, osteoarthritis, patellofemoral joint, pre-loading
Citation
Bourne, D. A., Moo, E. K., & Herzog, W. (2015). Cartilage and chondrocyte response to extreme muscular loading and impact loading: Can in vivo pre-load decrease impact-induced cell death? Clinical Biomechanics, 30(6), 537-545. doi:10.1016/j.clinbiomech.2015.04.009