Methylphenidate Effects in Attention-Deficit/Hyperactivity Disorder: Is Behavioural or Neuropsychological Data More Relevant?

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atmire.migration.oldid2449
dc.contributor.advisorHale, James Bradford
dc.contributor.authorCarmichael, Jessica Alexandra
dc.date.accessioned2014-09-04T20:31:01Z
dc.date.available2014-11-17T08:00:43Z
dc.date.issued2014-09-04
dc.date.submitted2014en
dc.description.abstractInconsistent methylphenidate (MPH) dose-response relationships are often observed in children with Attention-Deficit/Hyperactivity Disorder (ADHD). This study examined whether informant-reported behavioural criteria or “cool” executive/working memory (EWM) and “hot” self-regulation (SR) neuropsychological factors differentiated MPH responders from non-responders. Fifty-six children with physician-diagnosed ADHD underwent four-week randomized, double-blind, placebo-controlled MPH trials. Children were administered a battery of neuropsychological measures sensitive to ADHD to evaluate cognitive MPH response. Classroom observations and Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR) parent/teacher reports were used to evaluate behavioural MPH response. EWM/SR factor scores discriminated cognitive MPH responders from non-responders, as did DSM-IV-TR Hyperactive-Impulsive criteria. Univariate F tests and Wilks ƛ results for EWM, SR, and DSM-IV-TR Hyperactive-Impulsive measures suggest their potential utility in detecting MPH response, whereas DSM-IV-TR Inattentive criteria were less useful. Results suggest practitioners should consider neuropsychological test performance in conjunction with behavioural report of ADHD symptoms when considering MPH treatment response.en_US
dc.identifier.citationCarmichael, J. A. (2014). Methylphenidate Effects in Attention-Deficit/Hyperactivity Disorder: Is Behavioural or Neuropsychological Data More Relevant? (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/26897en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/26897
dc.identifier.urihttp://hdl.handle.net/11023/1721
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectEducational Psychology
dc.subject.classificationADHDen_US
dc.subject.classificationdiagnosisen_US
dc.subject.classificationneuropsychologyen_US
dc.subject.classificationBehaviouren_US
dc.subject.classificationMethylphenidateen_US
dc.titleMethylphenidate Effects in Attention-Deficit/Hyperactivity Disorder: Is Behavioural or Neuropsychological Data More Relevant?
dc.typemaster thesis
thesis.degree.disciplineEducational Psychology
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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