Does the plateau in the NIRS-derived [HHb] signal in the vastus lateralis represent the upper limit in O2 extraction during ramp incremental cycling?

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dc.contributor.advisorMurias, Juan M.
dc.contributor.authorInglis, Erin Calaine
dc.contributor.committeememberMillet, Guillaume Y.
dc.contributor.committeememberPassfield, Louis
dc.date2018-11
dc.date.accessioned2018-09-17T14:02:08Z
dc.date.available2018-09-17T14:02:08Z
dc.date.issued2018-09-10
dc.description.abstractOxygen (O2) extraction and O2 delivery represent the two critical components for muscle metabolism and have been extensively studied. The near-infrared spectroscopy (NIRS) derived O2 extraction signal ([HHb]) has been widely used for characterizing the peripheral response to exercise. Research examining this signal in response to ramp-incremental cycling has identified a linear increase followed by a plateau ([HHb]PLATEAU) prior to the achievement of maximal oxygen uptake (V̇O2max). Despite the common occurrence of this plateau, beyond speculation no research has been conducted to examine the underlying mechanisms causing the plateau in this signal. The studies in this thesis contribute to the understanding of the mechanisms that mediate the [HHb]PLATEAU by examining the maximal achievable level of O2 extraction at the end of a ramp-incremental test in different populations. In this two-part study 26 subjects were tested and divided into groups based on sex and training status. The results from the first part of this study demonstrated the existence of a reserve in O2 extraction and suggest that the [HHb]PLATEAU does not represent the upper limit of extraction in the vastus lateralis muscle. Additionally, the second part of this study revealed that sex and training status do not influence the amplitude of the reserve.en_US
dc.identifier.citationInglis, E. C. (2018). Does the plateau in the NIRS-derived [HHb] signal in the vastus lateralis represent the upper limit in O2 extraction during ramp incremental cycling? (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/32915en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/32915
dc.identifier.urihttp://hdl.handle.net/1880/107739
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.facultyKinesiology
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectblood flow
dc.subject[HHb]
dc.subjectnear-infrared spectroscopy
dc.subjectoxygen extraction
dc.subjectexercise
dc.subject.classificationPhysiologyen_US
dc.titleDoes the plateau in the NIRS-derived [HHb] signal in the vastus lateralis represent the upper limit in O2 extraction during ramp incremental cycling?
dc.typemaster thesis
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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