Acute Impaired Glucoregulation and Disrupted Gastrointestinal Hormone Secretion in Adolescents in Response to Caffeine-Containing and Nutritionally Fortified “Energy Shots”

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atmire.migration.oldid5382
dc.contributor.advisorShearer, Jane
dc.contributor.advisorHo, Josephine
dc.contributor.authorVirtanen, Heidi
dc.contributor.committeememberPacaud, Danièle
dc.contributor.committeememberReimer, Raylene
dc.contributor.committeememberMichelle, Jackman
dc.date.accessioned2017-03-06T18:10:30Z
dc.date.available2017-03-06T18:10:30Z
dc.date.issued2017
dc.date.submitted2017en
dc.description.abstractCaffeine-containing energy drinks (CCED) are beverages containing simple sugars, caffeine and mixtures of vitamin, mineral and/or herbal preparations which are aggressively marketed to adolescents and young adults. This study analyzed the metabolic impact of acute, non-nutritive sweetener-containing CCED consumption on glucoregulation and gut peptide response in adolescents, and how it is affected by genetic variance. CCED consumption induced acute insulin resistance following an oral glucose tolerance test when compared with placebo, with glucose and insulin concentrations rising by 15.8% and 73.0%, respectively. Glucagon-like peptide-1, gastric inhibitory peptide, C-peptide, and pancreatic peptide YY concentrations rose following caffeine and decaffeinated treatments when compared with placebo. Genetically fast caffeine metabolizers had exaggerated glucose and insulin curves following caffeine trials, while slow metabolizers were relatively unchanged. This response to CCED consumption could be detrimental to individuals predisposed to metabolic deficits. Results provoke further exploration into the mechanisms involved in this transient insulin resistance.en_US
dc.identifier.citationVirtanen, H. (2017). Acute Impaired Glucoregulation and Disrupted Gastrointestinal Hormone Secretion in Adolescents in Response to Caffeine-Containing and Nutritionally Fortified “Energy Shots” (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/24696en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/24696
dc.identifier.urihttp://hdl.handle.net/11023/3665
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.facultyKinesiology
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectGenetics
dc.subjectPhysiology
dc.subjectNutrition
dc.subjectPublic Health
dc.subject.otherdiabetes
dc.subject.otherenergy drinks
dc.subject.otherObesity
dc.subject.otherpediatrics
dc.subject.otherinsulin resistance
dc.titleAcute Impaired Glucoregulation and Disrupted Gastrointestinal Hormone Secretion in Adolescents in Response to Caffeine-Containing and Nutritionally Fortified “Energy Shots”
dc.typemaster thesis
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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