The impact of ventilator-associated pneumonia among prehospital intubated patients.

atmire.migration.oldid214
dc.contributor.advisorHenderson, Elizabeth
dc.contributor.authorLinton, Kathryn
dc.date.accessioned2012-08-16T20:04:59Z
dc.date.available2012-11-13T08:01:18Z
dc.date.issued2012-08-16
dc.date.submitted2012en
dc.description.abstractThe objective of this study was to determine if all-cause mortality and hospital length of stay among patients who develop ventilator-associated pneumonia (VAP) differs for patients intubated in the Prehospital setting compared to those intubated in the Emergency Department. A retrospective cohort design was employed and secondary data was retrieved from the local VAP Surveillance database and manual chart reviews. Intubated patients entered the cohort upon VAP diagnosis and exited upon death or hospital discharge. This study used data from three large inner-city adult hospitals within Calgary, Alberta Canada. The sample (n=193) consisted of all adult (>18 years old) patients that developed VAP in an Intensive Care Unit who were intubated either in the Prehospital or Emergency Department setting during the study period (January 01, 2005 and December 31, 2009). Patients in this study intubated in the Prehospital setting were very similar to patients intubated in the Emergency Department with regards to basic demographic and admission characteristics. This study provides several novel results about the association between endotracheal intubation (ETI) location and morbidity and mortality among patients who acquire VAP in the ICU. Patients who suffer severe illness or injury (APACHE II score >25) are more likely to die if they are intubated in the Prehospital setting compared to the Emergency Department (p=<0.001). Furthermore, Prehospital ETI patients who die, do so sooner than Emergency Department ETI patients; whereas Prehospital ETI patients who survive, have longer hospitalizations than their Emergency Department counterparts (p=<0.001). Perhaps preventing ETI in the Prehospital setting or postponing ETI until Emergency Department would result in decreased hospital mortality. Further research is required before this information should be used in a clinical setting.en_US
dc.identifier.citationLinton, K. (2012). The impact of ventilator-associated pneumonia among prehospital intubated patients. (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/28196en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/28196
dc.identifier.urihttp://hdl.handle.net/11023/150
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectMedical
dc.subjectEpidemiology
dc.subjectMedicine and Surgery
dc.subject.classificationVentilator-Associated Pneumoniaen_US
dc.subject.classificationIntubationen_US
dc.subject.classificationEmergency Departmenten_US
dc.subject.classificationPrehospitalen_US
dc.subject.classificationMortalityen_US
dc.titleThe impact of ventilator-associated pneumonia among prehospital intubated patients.
dc.typemaster thesis
thesis.degree.disciplineCommunity Health Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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