Evoked Responses to Affective Stimuli as a Marker for Reward System Dysfunction in Adolescents with Autism Spectrum Disorder (ASD)

Simple item page
atmire.migration.oldid5350
dc.contributor.advisorBray, Signe
dc.contributor.advisorProtzner, Andrea
dc.contributor.authorRivard, Keelin
dc.contributor.committeememberCurtin, Suzanne
dc.contributor.committeememberGraham, Susan
dc.contributor.committeememberMonchi, Oury
dc.date.accessioned2017-02-13T19:08:15Z
dc.date.available2017-02-13T19:08:15Z
dc.date.issued2017
dc.date.submitted2017en
dc.description.abstractThe core symptoms of autism spectrum disorder (ASD) may be related to atypical engagement of the brain’s reward system. We investigated whether visual reinforcers, images depicting restricted interests, are processed abnormally in ASD, as a marker for reward system dysfunction. We collected electroencephalography (EEG) while 20 ASD and 20 typically developing (TD) control participants, aged 14-20, performed a visual target detection task. We evaluated differences in the late positive potential (LPP), a marker for emotional processing, as well as trial-to-trial variability in the visual P1 response, which may indicate ‘noisier’ processing of visual reinforcers. We found greater LPP amplitude for high- and low-interest images, relative to neutral, with no significant group difference. In contrast, for the P1, we found overall greater amplitude and amplitude-variability in the ASD group that did not differentiate between conditions. This study provides new insight into processing of visual reinforcers in ASD. en_US
dc.identifier.citationRivard, K. (2017). Evoked Responses to Affective Stimuli as a Marker for Reward System Dysfunction in Adolescents with Autism Spectrum Disorder (ASD) (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/26000en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/26000
dc.identifier.urihttp://hdl.handle.net/11023/3651
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectPsychology--Clinical
dc.subject.otherEEG
dc.subject.otherReward
dc.subject.otherAutism
dc.titleEvoked Responses to Affective Stimuli as a Marker for Reward System Dysfunction in Adolescents with Autism Spectrum Disorder (ASD)
dc.typemaster thesis
thesis.degree.disciplineMedical Science
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
Files
Collections
Open Theses and Dissertations