The Feasibility of a Physical Activity Intervention for Advanced Multiple Myeloma Patients:  A Mixed Methods Study.

Albinati, Natalia Kara Renee

The Feasibility of a Physical Activity Intervention for Advanced Multiple Myeloma Patients: A Mixed Methods Study.

dc.contributor.advisor	Culos-Reed, Susan Nicole
dc.contributor.author	Albinati, Natalia Kara Renee
dc.contributor.committeemember	Abdul-Razzak, Amane
dc.contributor.committeemember	McDonough, Meghan H.
dc.contributor.committeemember	Gyurcsik, Nancy C.
dc.date	2019-11
dc.date.accessioned	2019-06-05T18:53:19Z
dc.date.available	2019-06-05T18:53:19Z
dc.date.issued	2019-06-04
dc.description.abstract	Purpose: The primary aims of the Physical Activity in Advanced Cancer Treatment (PAACT) intervention were to 1) examine the feasibility of a group- and home-based PA program for individuals with advance multiple myeloma (MM) and 2) qualitatively explore the patient’s experience in the program. Secondary aims were to obtain preliminary data on physical fitness and patient-reported outcomes. Methods: In this single-arm study, advanced MM patients (DS stage II-III) participated in a 12-week aerobic and resistance training exercise program, along with the option of a palliative care consultation. Participants attended once-weekly group exercise classes and received individualized home-based exercise booklets. Semi-structured interviews were conducted both midway and at the end of the program with a subset of participants and a thematic analysis approach was utilized. Results: In total, 19 MM patients were enrolled. The program was feasible as demonstrated by recruitment (34.5%), attendance at group classes (72.9%), attrition (15.8%) and safety outcomes (no adverse events). Thematic analysis revealed that the main facilitators were the exercise instructors and the supportive social environment. Barriers included side-effects of cancer treatments and a lack of motivation for home exercise. The main impacts were the perceived benefits to well-being with control over one’s health and exercise behaviour emerging as a core theme. Palliative care consultations were appreciated and helpful, although symptom burden did not always warrant palliative care. Conclusion: Group-and home-based exercise is feasible for advanced MM survivors. Participant experiences indicated that there were numerous perceived physical and mental benefits to participation. These findings may be used to inform the design and implementation of larger PA trials to examine the efficacy of PA interventions and palliative care in this population.	en_US
dc.identifier.citation	Albinati, N. K. R. (2019). The Feasibility of a Physical Activity Intervention for Advanced Multiple Myeloma Patients: A Mixed Methods Study (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca.	en_US
dc.identifier.doi	http://dx.doi.org/10.11575/PRISM/36620
dc.identifier.uri	http://hdl.handle.net/1880/110471
dc.language.iso	eng	en_US
dc.publisher.faculty	Kinesiology	en_US
dc.publisher.institution	University of Calgary	en
dc.rights	University of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.	en_US
dc.subject	Physical activity	en_US
dc.subject	Multiple Myeloma	en_US
dc.subject	Exercise	en_US
dc.subject	Intervention	en_US
dc.subject	Supportive cancer care	en_US
dc.subject	Advanced Cancer	en_US
dc.subject.classification	Education--Health	en_US
dc.subject.classification	Oncology	en_US
dc.title	The Feasibility of a Physical Activity Intervention for Advanced Multiple Myeloma Patients: A Mixed Methods Study.	en_US
dc.type	master thesis	en_US
thesis.degree.discipline	Kinesiology	en_US
thesis.degree.grantor	University of Calgary	en_US
thesis.degree.name	Master of Science (MSc)	en_US
ucalgary.item.requestcopy	true