Understanding How to Care about Indifference: A Multistep Approach to Apathy in Parkinson’s Disease

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dc.contributor.advisorHolroyd-Leduc, Jayna M.
dc.contributor.advisorGoodarzi, Zahra S.
dc.contributor.authorMele, Bria
dc.contributor.committeememberHanson, Heather
dc.contributor.committeememberPringsheim, Tamara M.
dc.contributor.committeememberIsmail, Zahinoor
dc.date2018-11
dc.date.accessioned2018-06-08T20:29:32Z
dc.date.available2018-06-08T20:29:32Z
dc.date.issued2018-06-08
dc.description.abstractBackground: Apathy is a complex and heterogeneous symptom in Parkinson’s disease (PD). It is present in 17 – 70% of persons with PD. Limited information is available on how to define, diagnose, and subsequently manage apathy in PD. Objectives: To firstly synthesize all available knowledge on apathy in PD to assess what is currently known and where gaps exist. Secondly, we aimed to assess barriers and facilitators to the use of this knowledge clinically. Methods: A scoping review based on literature from six databases and extensive grey literature search was completed, examining the diagnosis, treatment, and management of apathy in PD. In focus groups and interviews with stakeholders, we assessed barriers and facilitators to the use of this knowledge. Results: A large body of literature exists on apathy in PD, however key gaps limit the use of knowledge. Gaps include the lack of an accepted apathy definition and limited treatment options. Health care practitioners feel limited in their ability to diagnose apathy without validated screening–tools. Patients and caregivers identified awareness of apathy and planning their days as key facilitators to diagnosis and management. Conclusions: Our findings highlight the importance of developing a broad understanding of available literature and the associated gaps, and the key role that stakeholders play in identifying where further research is required most. Our findings will aid in future research directed at the development of an apathy definition and management focused on non-pharmacological interventions.en_US
dc.identifier.citationMele, B. (2018). Understanding How to Care about Indifference: A Multistep Approach to Apathy in Parkinson’s Disease (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/31975en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/31975
dc.identifier.urihttp://hdl.handle.net/1880/106747
dc.language.isoeng
dc.publisher.facultyCumming School of Medicine
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectParkinson's Disease
dc.subjectApathy
dc.subjectDiagnosis
dc.subjectTreatment
dc.subject.classificationMedicine and Surgeryen_US
dc.subject.classificationMental Healthen_US
dc.titleUnderstanding How to Care about Indifference: A Multistep Approach to Apathy in Parkinson’s Disease
dc.typemaster thesis
thesis.degree.disciplineCommunity Health Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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