Cumming School of Medicine

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https://prism.ucalgary.ca/handle/1880/100023

The University of Calgary Faculty of Medicine was established in 1967 and renamed the Cumming School of Medicine in 2014. The Cumming School of Medicine is a national research leader in brain and mental health, chronic diseases and cardiovascular sciences.

Cumming School of Medicine

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Open Access
2021 (34th Annual) Sebastian K. Littmann Research Day Abstracts
(2021-03-05) University of Calgary
Abstract booklet and program from the Department of Psychiatry's Annual Research Day held March 5, 2021.
Open Access
2022 (35th Annual) Sebastian K. Littmann Research Day Abstracts
(University of Calgary, 2022-03-04) Patten, Scott
Abstracts from the 35th annual Sebatian K. Littmann Research Day.
Open Access
2023 Mathison-Littmann Research Day Abstracts
(2023-03-03) Patten, Scott Burton
Abstracts from the 2023 Sebastian K. Littmann Research Day at the University of Calgary.
Open Access
2SLGBTQQIA+ Experiences of Intimate Partner Abuse and Help-Seeking: An Intersectional Scoping Review
(2023-08-08) Kurbatfinski, Stefan; Whitehead, Jessica; Hodge, Lee; Ulicki, Noah; Madaan, Ridham; Henry, Richard S.; Parente, Isi; Kumbah, Ophilia; Pino, Fritz; Krentz, Hartmut B.; Morris, Martin; Santinele Martino, Alan; Maurer, Katherine; Marshall, Zack
Background Intimate partner abuse (IPA) encompasses various forms of abuse between intimate partners, including physical, sexual, emotional, financial, legal, cultural, spiritual, religious, and other types of violence. Recent studies challenge cisgender heteronormative representations of IPA by revealing that the prevalence of IPA between Two-Spirit, lesbian, gay, bisexual, trans, queer, questioning, intersex, asexual, and other sexual or gender minority (2SLGBTQQIA+) partners is similar to heterosexual IPA. However, discriminatory beliefs enacted through homophobia, transphobia, racism, sexism, and colonialism uniquely influence 2SLGBTQQIA+ experiences of IPA. Moreover, the lack of service availability and diversity specifically tailored to 2SLGBTQQIA+ communities further complicate efforts to address IPA, exacerbating inequities and impacting well-being. Objectives This scoping review aimed to achieve three main objectives: 1. Identify knowledge strengths and gaps related to IPA among 2SLGBTQQIA+ people; 2. Describe the help-seeking efforts and experiences of 2SLGBTQQIA+ people who have encountered IPA, including interactions with informal supports (e.g., friends, family members) and formal services (e.g., police, counsellors); and 3. Provide evidence-based recommendations to enhance service responsiveness to 2SLGBTQQIA+ communities. Methodology The review protocol was registered on PROSPERO (#CRD42020139639) and followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews (PRISMA-ScR) guidelines. We included qualitative, quantitative, and mixed-method studies that examined help-seeking patterns and outcomes of 2SLGBTQQIA+ people who experience and/or use IPA against partners. A comprehensive search was conducted across multiple databases, including Medline, Embase, PsycInfo, Scopus, CINAHL, Genderwatch, and Social Science Abstracts. From the 5,827 initial results, 1,790 references were screened on full text. A total of 703 peer-reviewed studies focused on 2SLGBTQQIA+ IPA, and of those, 142 specifically examined help-seeking and 2SLGBTQQIA+ IPA. Each reference was screened by at least two members of the review team and data extraction was supported by four authors. Findings were categorized by sexual and gender identity group when possible, with further consideration of intersectionality. Results Most studies examined mixed sexual and gender minority (SGM) samples without providing stratified results. Community-specific studies on IPA were more likely to focus on lesbians, and trans people, followed by studies with bisexual participants, gay men, and Two-Spirit people. Notably, no studies included intersex participants, and there were no specific results available for individuals questioning their sexual and/or gender identity or those who identified as asexual. Emotional abuse or violence was commonly reported as the most prevalent form of IPA among LGBT individuals. Bisexual men and women seemed to experience a higher prevalence of IPA compared to lesbians or gay men. Many studies revealed that 2SLGBTQQIA+ individuals were often unaware that the control, violence, or manipulation they experienced in their intimate relationships could be classified as abuse, acting as a barrier to seeking support or leaving abusive relationships. This lack of recognition was often attributed to gendered discourses that centre cisheteronormative relationships and overlook 2SLGBTQQIA+ specific forms of abuse. Other significant barriers across all groups included a lack of knowledge about available services, the absence of 2SLGBTQQIA+-specific services (and services providers), and anticipated or enacted discrimination from service providers. Negative experiences with accessing police services were commonly reported by many identity groups, while LGBT individuals also expressed dissatisfaction with legal services, indicating limited opportunities for seeking justice. Counsellors and friends were often regarded as positive sources of support. Key Messages Based on this review, the following areas require attention: 1. Critical changes are needed to gender-based violence services, particularly violence shelters, to properly respond to 2SLGBTQQIA+ communities. Many services perpetuate gender norms and engage in discriminatory actions that impede adequate support, including a significant service gap for both cis and trans male-identified individuals. 2. Ensuring justice for 2SLGBTQQIA+ people who experience violence is essential, necessitating attention to formal legal systems, policing, and transformative justice. 3. Counselling services are a strength and a valuable resource for 2SLGBTQQIA+ people in relation to IPA. It is crucial to support this sector, including measures to reduce individual costs and increase accessibility. 4. Increased education and training are needed for service providers working in formal services to reduce stigma and misconceptions and improve service interactions. 5. Educational curricula in schools should be adapted to include 2SLGBTQQIA+ IPA, enabling individuals to recognize experiences of abuse and support one another. 6. Informal support from friends is a crucial resource, and its effectiveness could be enhanced by establishing stronger connections to collective care initiatives. 7. Research and service design need to meaningfully integrate intersectional frameworks that better respond to the full diversity of 2SLGBTQQIA+ communities. 8. There is an urgent need for a collective impact model that addresses abuse prevention, coordinated service navigation pathways, evaluation of informal and formal supports, shared values (intersectional and trauma-informed care), and increased funding. By implementing these recommendations, progress can be made in addressing the gaps and challenges identified in this review leading to improved IPA supports and services for 2SLGBTQQIA+ communities.
Open Access
350 Needs in Low Resource Settings
(Presented at Med-e-tel 2005 Conference in Luxembourg, 2005-04-07) Zolfo, M.; Lynen, L.; Huyst, V.; Arnould, L.
eHealth and Education: Telemedicine is a way to deliver health care in remote areas. Meeting the goal of accessing health information in developing countries and facing the necessity to scale up the use of antiretrovirals (ARVs) in low resource settings, the Institute of Tropical Medicine, Antwerp (ITMA) set up a computer aided training programme for health providers, working in disadvantaged areas. Expert advice from HIV/AIDS specialists about ARVs and management of Opportunistic Infections (OIs) has been offered to colleagues working in different resource limited settings.
Open Access
4th Research and Development Framework Programme (1994-1998). Health Telematics Projects: Final Report.
(European Comission Directorate General Information Society, 2001-11) Rubis Project (Editor); Kemi-Tornio Polytechnic (Editor); Oulu Polytechnic (Editor); Oulu University (Editor)
Overview of Health Telematics projects funded by the Healthcare sector of the Telematics Applications Programme (TAP).
Open Access
6-STEPPs: A Modular Tool to Facilitate Clinician Participation in Fair Decisions for Funding New Cancer Drugs
(2008) Sinclair, Shane; Browman, George P.; Manns, Braden; Hagen, Neil; Chambers, Carole R.; Simon, Anita
To design a tool to assist clinician participation with cancer drug funding decisions. Public policy-makers and insurers are struggling with funding decisions regarding increasingly expensive new cancer drugs. Increasingly, oncologists are contributing to the process of review that leads to such decisions. We were asked to design a system for ranking new cancer drugs for priority-based funding decisions.
Open Access
An 8-year-old child with delayed diagnosis of Netherton syndrome
(Hindawi, 2018-01-30) Leung, AK; Barankin, B; Leong, KF
We report an 8-year-old boy with Netherton syndrome who was misdiagnosed and treated as severe atopic dermatitis. The diagnosis of Netherton syndrome was not made until the child was 8 years of age. We discuss the pitfalls in the diagnosis and alert physicians to the proper and early diagnosis of this syndrome. The child was treated with a low dose (0.25 mg/kg) of oral acitretin and a topical moisturizer with marked improvement of his skin and pruritus in 2 months. At 6-month follow-up, the skin was almost clear of erythema and scaling, and the hair was longer and stronger. The dose of acitretin was reduced to 0.12 mg/kg for another 6 months and then discontinued.
Open Access
A Functional Magnetic Resonance Imaging Study to Investigate the Utility of a Picture Imagination Task in Investigating Neural Responses in Patients with Chronic Musculoskeletal Pain to Daily Physical Activity Photographs
(Public Library of Science (PLoS), 2015-10-23) Taylor, Ann M.; Harris, Ashley D.; Varnava, Alice; Phillips, Rhiannon; Taylor, Justin O.; Hughes, Owen; Wilkes, Antony R.; Hall, Judith E.; Wise, Richard G.
Pain-related anxiety and fear are associated with increased difficulties in attention, increased awareness of pain, impaired disengagement from pain, and can moderate the effects of attentional coping attempts. Accurately assessing the direct impact of pain-related anxiety and fear on pain behavior has proved difficult. Studies have demonstrated no or limited influence of pain-related fear and anxiety on behavior but this may be due to inherent problems with the scales used. Neuroimaging has improved the understanding of neural processes underlying the factors that influence pain perception. This study aimed to establish if a Picture and Imagination Task (PIT), largely developed from the Photographs of Daily Activity (PHODA) assessment tool, could help explore how people living with chronic pain process information about daily activities. Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) was used to compare brain responses in patients with chronic musculoskeletal pain (CMSKP) (n = 15) and healthy controls (n = 15). Subjects were asked to imagine how they would feel mentally and physically if asked to perform daily activities illustrated in PIT. The results found that a number of regions involved in pain processing saw increased BOLD activation in patients compared with controls when undertaking the task and included the insula, anterior cingulate cortex, thalamus and inferior and superior parietal cortices. Similarly, increased BOLD responses in patients compared to controls in the frontal pole, paracingulate and the supplementary motor cortex may be suggestive of a memory component to the responses The amygdala, orbitofrontal cortex, substantia nigra/ventral tegmentum, putamen, thalamus, pallidum, inferior parietal (supramarginal and angular gyrus) and cingulate cortex were also seen to have greater differences in BOLD signal changes in patients compared with controls and many of these regions are also associated with general phobic responses. Therefore, we suggest that PIT is a useful task to explore pain-and movement-related anxiety and fear in fMRI studies. Regions in the Default Mode Network remained active or were less deactivated during the PIT task in patients with CMSKP compared to healthy controls supporting the contention that the DMN is abnormal in patients with CMSKP.
Open Access
A Longitudinal Seroepidemiology Study to Evaluate Antibody Response to SARS-CoV-2 Virus and Vaccination in Children in Calgary, Canada from July 2020 to September 2022.
(Canadian Immunization Conference, 2023-04-19) Doucette, Emily Jayne; Kellner, James Duncan
Introduction: Measurement of SARS-CoV-2 antibody seropositivity is important to accurately understand exposure to infection and/or vaccination in populations. Methods: A cohort of children with or without prior SARS-CoV-2 infections was enrolled in Calgary, Canada in 2020. Venous blood was sampled 4 times from July 2020 to April 2022 for SARS-CoV-2 nucleocapsid and spike antibodies, with an additional 5th visit in the fall of 2022. Demographic and clinical information was obtained including SARS-CoV-2 test results and vaccination records. Results and analysis: 1035 children were enrolled and 88.9% completed 4 visits; median age 9 years (IQR: 5,13); 519 (50.1%) female; and 815 (78.7%) Caucasian. 477 (46.1%) participants attended Visit 5. Before enrollment, 118 (11.4%) had confirmed or probable SARS-CoV-2 infection. By September 2022, the total cumulative percentage of previously uninfected participants diagnosed with COVID-19 was 53.9% by Visit 5. (0/917 (0%), 15/873 (1.7%), 31/837 (3.7%), 280/820 (34.1%), and 63/439 (14.4%) at Visits 1-5, respectively). Nucleocapsid antibody seropositivity declined to 18.0% after more than 200 days after diagnosis. In contrast, spike antibodies remained elevated in 97.6% of unvaccinated children after more than 400 days after diagnosis. By September 2022, 97.1% (232/239) of children 12 years and older, 85.9% (171/199) of children 5-11, and 15.4% (6/39) of children under 5 received at least 1 dose of vaccine. At that time, all 409 vaccinated children had spike antibodies, compared with 38/64 (59.4%) of unvaccinated children (P<0.001 for comparison of proportions). Conclusions: By September 2022, most children in the study had a serologic response against the SARS-CoV-2 virus from infection and/or vaccination, with unvaccinated children much less likely to have a serologic response. Ongoing studies of serologic status are needed to estimate population levels of virus exposure and durability of antibody response after infection and/or vaccination.
Open Access
Absence of clinical relationship between oxidized low density lipoproteins and diabetic peripheral neuropathy: a case control study
(BioMed Central, 2014-02-12) Rosales-Hernandez, Alma; Cheung, Audrey; Podgorny, Peter; Chan, Cynthia; Toth, Cory
Open Access
Absent right and persistent left superior vena cava: troubleshooting during a challenging pacemaker implant: a case report
(BioMed Central, 2014-07-21) Jacques Rizkallah; John Burgess; Kuriachan, Vikas P.
Open Access
Abstract booklet from the 2019 Sebastian K. Littmann Research Day
(2019-03-01) Patten, Scott B.
Open Access
Abstracts from the 2001 Sebastian K. Littmann Research Day
(2007-04-18T20:29:37Z)
Open Access
Abstracts from the 2002 Sebastian K. Littmann Research Day
(2007-04-21T19:56:25Z)
Open Access
Abstracts from the 2003 Sebastian K. Littmann Research Day
(2007-04-21T19:57:22Z)
Open Access
Abstracts from the 2004 Sebastian K. Littmann Research Day
(2007-04-21T19:58:23Z)
Open Access
Abstracts from the 2005 Sebastian K. Littmann Research Day
(2007-04-21T19:59:19Z)
Open Access
Abstracts from the 2006 Sebastian K. Littmann Research Day
(2007-04-21T20:00:37Z)
Open Access
Abstracts from the 2007 Sebastian K. Littmann Research Day
(2007-03-09T01:13:00Z)
These are the abstracts from the 20th Annual Sebastian K. Littmann Research Day. The event was held at the Village Park Inn in Calgary Alberta on March 2, 2007.