Meningitis Due to Ampicillin-and Chloramphenicol-Resistant Haemophilus influenzae Type B in Canada. Case Report and Review
Date
1990-01-01
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The first report of a case of ampicillin- and chloramphenicol-resistant Haemophilus influenzae type b invasive infection in Canada is described in a four-month-old male with meningitis. He was treated with cefotaxime 200 mg/kg/day divided every 6 h and dexamethasone 0.6 mg/kg/day divided every 6 h, eventually recovering after a complicated course. Follow-up at 21 months showed mild to moderate global developmental delay. While chloramphenicol resistance is rare in North America, a case of meningitis initially unresponsive to ampicillin and chloramphenicol must be considered suspect for resistance. Third generation cephalosporins should be used for resistant cases.
Description
Keywords
Citation
Amin Kabani, Ari Joffe, Gisele Cadrain, and Taj Jadavji, “Meningitis Due to Ampicillin-and Chloramphenicol-Resistant Haemophilus influenzae Type B in Canada. Case Report and Review,” Canadian Journal of Infectious Diseases, vol. 1, no. 3, pp. 92-96, 1990. doi:10.1155/1990/691734