Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial
| dc.contributor.author | Garcia Guerra, Gonzalo | |
| dc.contributor.author | Joffe, Ari R | |
| dc.contributor.author | Sheppard, Cathy | |
| dc.contributor.author | Hewson, Krista | |
| dc.contributor.author | Dinu, Irina A | |
| dc.contributor.author | Hajihosseini, Morteza | |
| dc.contributor.author | deCaen, Allan | |
| dc.contributor.author | Jou, Hsing | |
| dc.contributor.author | Hartling, Lisa | |
| dc.contributor.author | Vohra, Sunita | |
| dc.date.accessioned | 2021-01-17T01:04:08Z | |
| dc.date.available | 2021-01-17T01:04:08Z | |
| dc.date.issued | 2021-01-12 | |
| dc.date.updated | 2021-01-17T01:04:07Z | |
| dc.description.abstract | Abstract Objective To demonstrate feasibility of a music medicine intervention trial in pediatric intensive care and to obtain information on sedation and analgesia dose variation to plan a larger trial. Material and methods Pilot randomized controlled trial (RCT) was conducted at the Stollery Children’s Hospital general and cardiac intensive care units (PICU/PCICU). The study included children 1 month to 16 years of age on mechanical ventilation and receiving sedation drugs. Patients were randomized in a 1:1:1 ratio to music, noise cancellation or control. The music group received classical music for 30 min three times/day using headphones. The noise cancellation group received the same intervention but with no music. The control group received usual care. Results A total of 60 patients were included. Average enrollment rate was 4.8 patients/month, with a consent rate of 69%. Protocol adherence was achieved with patients receiving > 80% of the interventions. Overall mean (SD) daily Sedation Intensity Score was 52.4 (30.3) with a mean (SD) sedation frequency of 9.75 (7.21) PRN doses per day. There was a small but statistically significant decrease in heart rate at the beginning of the music intervention. There were no study related adverse events. Eighty-eight percent of the parents thought the headphones were comfortable; 73% described their child more settled during the intervention. Conclusions This pilot RCT has demonstrated the feasibility of a music medicine intervention in critically ill children. The study has also provided the necessary information to plan a larger trial. | |
| dc.identifier.citation | Journal of Intensive Care. 2021 Jan 12;9(1):7 | |
| dc.identifier.doi | https://doi.org/10.1186/s40560-020-00523-7 | |
| dc.identifier.uri | http://hdl.handle.net/1880/112981 | |
| dc.identifier.uri | https://doi.org/10.11575/PRISM/44009 | |
| dc.language.rfc3066 | en | |
| dc.rights.holder | The Author(s) | |
| dc.title | Music Use for Sedation in Critically ill Children (MUSiCC trial): a pilot randomized controlled trial | |
| dc.type | Journal Article |