Vitamin D Deficiency and Antenatal and Postpartum Depression: A Systematic Review

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dc.contributor.authorAghajafari, Fariba
dc.contributor.authorLetourneau, Nicole Lyn
dc.contributor.authorMahinpey, Newsha
dc.contributor.authorCosic, Nela
dc.contributor.authorGiesbrecht, G. F.
dc.date.accessioned2018-12-03T21:33:36Z
dc.date.available2018-12-03T21:33:36Z
dc.date.issued2018-04-12
dc.description.abstractVitamin D has been implicated in antenatal depression (AD) and postpartum depression (PPD) in many studies; however, results have been inconsistent due to the complexity of this association. We searched the MEDLINE, Embase, PsycINFO, and Maternity and Infant Care databases for literature addressing associations between vitamin D and AD and PPD. Two independent authors reviewed titles and abstracts of the search results and selected studies for full review. Data were extracted, and a quality rating was done using the Newcastle–Ottawa Scale (NOS) on the selected studies. A total of 239 studies were identified; 14 were included in the review. The quality assessment of the included studies ranged from moderate to high. Of the studies on PPD, five of nine (55%) showed a significant association between vitamin D and PPD. Five of seven (71%) studies on AD showed a significant association with vitamin D status. As the included studies used different effect estimates and statistical analyses to report the association, it was not possible to transform the existing data into one single effect measure to employ meta-analytic techniques. While results of this systematic review vary, they indicate a significant association between vitamin D status and AD and PD.en_US
dc.identifier.citationAghajafari, F., Letourneau, N. L., Mahinpey, N., Cosic, N., & Giesbrecht, G. F. (2018). Vitamin D Deficiency and Antenatal and Postpartum Depression : A Systematic Review. "Nutrients" (2018), 10, 478, 1–15. https://doi.org/10.3390/nu10040478en_US
dc.identifier.doidoi:10.3390/nu10040478en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/34675
dc.identifier.urihttp://hdl.handle.net/1880/109224
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.publisher.departmentPaediatricsen_US
dc.publisher.facultyCumming School of Medicineen_US
dc.publisher.hasversionPublisher's versionen_US
dc.publisher.institutionUniversity of Calgaryen_US
dc.publisher.policyhttps://www.mdpi.com/about/openaccessen_US
dc.relation.ispartofseries10(4), 478en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.subjectvitamin Den_US
dc.subject25(OH)Den_US
dc.subjectantenatal depressionen_US
dc.subjectpostnatal depressionen_US
dc.subjectdepressionen_US
dc.subjectpregnancyen_US
dc.titleVitamin D Deficiency and Antenatal and Postpartum Depression: A Systematic Reviewen_US
dc.typejournal articleen_US
dc.typeotheren_US
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