Iron Oxide as an MRI Contrast Agent for Cell Tracking

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dc.contributor.authorKorchinski, Daniel
dc.contributor.authorTaha, Mai
dc.contributor.authorYang, Runze
dc.contributor.authorNathoo, Nabeela
dc.contributor.authorDunn, Jeff F.
dc.date.accessioned2016-03-24T15:57:39Z
dc.date.available2016-03-24T15:57:39Z
dc.date.issued2015-08-19
dc.description.abstractIron oxide contrast agents have been combined with magnetic resonance imaging for cell tracking. In this review, we discuss coating properties and provide an overview of ex vivo and in vivo labeling of different cell types, including stem cells, red blood cells, and monocytes/macrophages. Furthermore, we provide examples of applications of cell tracking with iron contrast agents in stroke, multiple sclerosis, cancer, arteriovenous malformations, and aortic and cerebral aneurysms. Attempts at quantifying iron oxide concentrations and other vascular properties are examined. We advise on designing studies using iron contrast agents including methods for validation.en_US
dc.description.grantingagencyAlberta Innovates Health Solutions; National Sciences and Engineering Research Council of Canadaen_US
dc.description.refereedYesen_US
dc.identifier.citationKorchinski, D. J., M. A. Taha, Y. Runze, N. Nathoo and J. F. Dunn. (2015). Iron oxide as an MRI contrast agent for cell tracking. Magnetic Resonance Insights. 8:15-29.en_US
dc.identifier.doi10.4137/MRI.S23557
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/33512
dc.identifier.issn1178-623X
dc.identifier.urihttp://hdl.handle.net/1880/51122
dc.language.isoenen_US
dc.publisherLibertas Academicaen_US
dc.publisher.departmentRadiologyen_US
dc.publisher.facultyMedicineen_US
dc.publisher.institutionUniversity of Calgaryen_US
dc.publisher.urlhttp://www.la-press.com/en_US
dc.relation.ispartofseriesMagnetic Resonance Insights;
dc.subjectmagnetic resonance imagingen_US
dc.subjectiron oxideen_US
dc.subjectcontrast agenten_US
dc.subjectcell trackingen_US
dc.titleIron Oxide as an MRI Contrast Agent for Cell Trackingen_US
dc.typejournal article
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