Neonatal Abdominal Hemangiomatosis: Propranolol beyond Infantile Hemangioma

dc.contributor.authorNip, Siu Ying Angel
dc.contributor.authorHon, Kam Lun
dc.contributor.authorLeung, Wing Kwan Alex
dc.contributor.authorLeung, Alexander K. C.
dc.contributor.authorChoi, Paul C. L.
dc.date.accessioned2018-09-27T11:25:14Z
dc.date.available2018-09-27T11:25:14Z
dc.date.issued2016-03-27
dc.date.updated2018-09-27T11:25:14Z
dc.description.abstractHemangioma is the most common vascular tumor of infancy; presentation is often as cutaneous infantile hemangioma (IH). Cutaneous hemangioma is a clinical diagnosis. Most IHs follow a benign course, with complete involution without treatment in the majority of cases. Visceral hemangioma often involves the liver and manifests as a life-threatening disorder. Hepatic hemangiomas may be associated with high output cardiac failure, coagulopathy, and hepatomegaly which generally develop between 1 and 16 weeks of age. Mortality has been reportedly high without treatment. We report a rare case of a male infant with neonatal hemangiomatosis with diffuse peritoneal involvement, which mimicked a malignant-looking tumor on imaging, and discuss therapeutic options and efficacy. Propranolol is efficacious for IH but generally not useful for other forms of vascular hemangiomas, tumors, and malformations. In our case of neonatal peritoneal hemangiomatosis, propranolol appears to have halted the growth and possibly expedite the involution of the hemangiomatosis without other treatments.
dc.description.versionPeer Reviewed
dc.identifier.citationSiu Ying Angel Nip, Kam Lun Hon, Wing Kwan Alex Leung, Alexander K. C. Leung, and Paul C. L. Choi, “Neonatal Abdominal Hemangiomatosis: Propranolol beyond Infantile Hemangioma,” Case Reports in Pediatrics, vol. 2016, Article ID 9803975, 4 pages, 2016. doi:10.1155/2016/9803975
dc.identifier.doihttps://doi.org/10.1155/2016/9803975
dc.identifier.urihttp://hdl.handle.net/1880/108139
dc.language.rfc3066en
dc.rights.holderCopyright © 2016 Siu Ying Angel Nip et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleNeonatal Abdominal Hemangiomatosis: Propranolol beyond Infantile Hemangioma
dc.typeJournal Article
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