Factors related to dropout in integrative oncology clinical trials: interim analysis of an ongoing comparative effectiveness trial of mindfulness-based cancer recovery and Tai chi/Qigong for cancer health (The MATCH study)

dc.contributor.authorOberoi, Devesh
dc.contributor.authorPiedalue, Katherine-Ann L
dc.contributor.authorPirbhai, Hassan
dc.contributor.authorGuirguis, Steven
dc.contributor.authorSanta Mina, Daniel
dc.contributor.authorCarlson, Linda E
dc.date.accessioned2020-07-19T00:06:57Z
dc.date.available2020-07-19T00:06:57Z
dc.date.issued2020-07-17
dc.date.updated2020-07-19T00:06:57Z
dc.description.abstractAbstract Objective To examine the factors associated with loss to follow-up (LTFU) in an ongoing preference-based randomized waitlist controlled trial of mindfulness-based cancer recovery (MBCR) and Taichi/Qigong (TCQ) for cancer survivors (the MATCH Study). Hierarchical logistic regression was used to determine the factors associated with LTFU. Predictors included adherence to treatment, preference vs. randomized, type of intervention (MBCR vs. TCQ) and program timing (immediate {IM} vs. waitlist control {WLC} group). Results Data indicated that randomization to the WLC group and, once in the intervention, low adherence were the main predictors of LTFU. Participants in the WLC group were 4 times more likely to be LTFU post-randomization [OR 3.96, 95% CI 2.08–7.56, p < 0.005] than those in the IM group. Participants showing low adherence to treatment were 6 times more likely for LTFU post-intervention [5.87 (2.57–13.400; p < 0.005] and 4 times more likely for LTFU 6 months post-intervention [OR 3.93, 95% CI 1.53–10.02, p = 0.01].
dc.identifier.citationBMC Research Notes. 2020 Jul 17;13(1):342
dc.identifier.doihttps://doi.org/10.1186/s13104-020-05172-5
dc.identifier.urihttp://hdl.handle.net/1880/112316
dc.language.rfc3066en
dc.rights.holderThe Author(s)
dc.titleFactors related to dropout in integrative oncology clinical trials: interim analysis of an ongoing comparative effectiveness trial of mindfulness-based cancer recovery and Tai chi/Qigong for cancer health (The MATCH study)
dc.typeJournal Article
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