The Use of Regenerative Medicine in the Management of Invasive Bladder Cancer

Simple item page
dc.contributor.authorHyndman, Matthew E.
dc.contributor.authorKaye, Deborah
dc.contributor.authorField, Nicholas C.
dc.contributor.authorLawson, Keith A.
dc.contributor.authorSmith, Norm D.
dc.contributor.authorSteinberg, Gary D.
dc.contributor.authorSchoenberg, Mark P.
dc.contributor.authorBivalacqua, Trinity J.
dc.date.accessioned2018-09-27T11:48:27Z
dc.date.available2018-09-27T11:48:27Z
dc.date.issued2012-08-27
dc.date.updated2018-09-27T11:48:27Z
dc.description.abstractMuscle invasive and recurrent nonmuscle invasive bladder cancers have been traditionally treated with a radical cystectomy and urinary diversion. The urinary diversion is generally accomplished through the creation of an incontinent ileal conduit, continent catheterizable reservoir, or orthotopic neobladder utilizing small or large intestine. While radical extirpation of the bladder is often successful from an oncological perspective, there is a significant morbidity associated with enteric interposition within the genitourinary tract. Therefore, there is a great opportunity to decrease the morbidity of the surgical management of bladder cancer through utilization of novel technologies for creating a urinary diversion without the use of intestine. Clinical trials using neourinary conduits (NUC) seeded with autologous smooth muscle cells are currently in progress and may represent a significant surgical advance, potentially eliminating the complications associated with the use of gastrointestinal segments in the urinary reconstruction, simplifying the surgical procedure, and greatly facilitating recovery from cystectomy.
dc.description.versionPeer Reviewed
dc.identifier.citationMatthew E. Hyndman, Deborah Kaye, Nicholas C. Field, et al., “The Use of Regenerative Medicine in the Management of Invasive Bladder Cancer,” Advances in Urology, vol. 2012, Article ID 653652, 7 pages, 2012. doi:10.1155/2012/653652
dc.identifier.doihttps://doi.org/10.1155/2012/653652
dc.identifier.urihttp://hdl.handle.net/1880/108329
dc.language.rfc3066en
dc.rights.holderCopyright © 2012 Matthew E. Hyndman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleThe Use of Regenerative Medicine in the Management of Invasive Bladder Cancer
dc.typeJournal Article
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
AU.2012.653652.pdf
Size:
497.11 KB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
0 B
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Open Access Publications