Modular Development of Gray Matter in Childhood and Adolescence

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atmire.migration.oldid3386
dc.contributor.advisorBray, Signe
dc.contributor.authorKrongold, Mark
dc.date.accessioned2015-07-13T16:53:48Z
dc.date.available2015-11-20T08:00:27Z
dc.date.issued2015-07-13
dc.date.submitted2015en
dc.description.abstractThe brain is becoming increasingly understood by its networks rather than regional architecture. Understanding the development of networks in the healthy human brain during childhood and adolescence is an important foundational step in determining what may go wrong in neurodevelopmental disorders. Moreover, it has been hypothesized that networks of functionally coupled regions may develop in parallel. In this thesis regions of the cerebral cortex undergoing synchronized development in anatomical structure were found and described. The findings indicated that cortical thickness, surface area, and volume underwent different developmental trajectories and showed differential synchronized developmental patterns. Cortical thickness based modules were distributed while surface area and volume based modules showed anterior to posterior organization. Additionally, comparisons between developmental modules and well-established functional networks in the brain found only partial overlap. This suggests that neuronal networks do not singularly arise from similar development of cortical regions.en_US
dc.identifier.citationKrongold, M. (2015). Modular Development of Gray Matter in Childhood and Adolescence (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/26974en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/26974
dc.identifier.urihttp://hdl.handle.net/11023/2353
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectNeuroscience
dc.subjectHuman Development
dc.subject.classificationDevelopmenten_US
dc.subject.classificationCerebral Cortexen_US
dc.subject.classificationChildhooden_US
dc.subject.classificationNeuroscienceen_US
dc.subject.classificationMRIen_US
dc.subject.classificationNeuronal Networksen_US
dc.subject.classificationNeuroimagingen_US
dc.titleModular Development of Gray Matter in Childhood and Adolescence
dc.typemaster thesis
thesis.degree.disciplineBiomedical Engineering
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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