Epilepsy Surgery Series: A Study of 502 Consecutive Patients from a Developing Country

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dc.contributor.authorAlsemari, Abdulaziz
dc.contributor.authorAl-Otaibi, Faisal
dc.contributor.authorBaz, Salah
dc.contributor.authorAlthubaiti, Ibrahim
dc.contributor.authorAldhalaan, Hisham
dc.contributor.authorMacDonald, David
dc.contributor.authorAbalkhail, Tareq
dc.contributor.authorFiol, Miguel E.
dc.contributor.authorAlyamani, Suad
dc.contributor.authorChedrawi, Aziza
dc.contributor.authorLeblanc, Frank
dc.contributor.authorParrent, Andrew
dc.contributor.authorMaclean, Donald
dc.contributor.authorGirvin, John
dc.date.accessioned2018-09-27T11:39:35Z
dc.date.available2018-09-27T11:39:35Z
dc.date.issued2014-01-30
dc.date.updated2018-09-27T11:39:34Z
dc.description.abstractPurpose. To review the postoperative seizure outcomes of patients that underwent surgery for epilepsy at King Faisal Specialist Hospital & Research Centre (KFSHRC). Methods. A descriptive retrospective study for 502 patients operated on for medically intractable epilepsy between 1998 and 2012. The surgical outcome was measured using the ILAE criteria. Results. The epilepsy surgery outcome for temporal lobe epilepsy surgery (ILAE classes 1, 2, and 3) at 12, 36, and 60 months is 79.6%, 74.2%, and 67%, respectively. The favorable 12- and 36-month outcomes for frontal lobe epilepsy surgery are 62% and 52%, respectively. For both parietal and occipital epilepsy lobe surgeries the 12- and 36-month outcomes are 67%. For multilobar epilepsy surgery, the 12- and 36-month outcomes are 65% and 50%, respectively. The 12- and 36-month outcomes for functional hemispherectomy epilepsy surgery are 64.2% and 63%, respectively. According to histopathology diagnosis, mesiotemporal sclerosis (MTS) and benign CNS tumors had the best favorable outcome after surgery at 1 year (77.27% and 84.3%, resp.,) and 3 years (76% and 75%, resp.,). The least favorable seizure-free outcome after 3 years occurred in cases with dual pathology (66.6%). Thirty-four epilepsy patients with normal magnetic resonance imaging (MRI) brain scans were surgically treated. The first- and third-year epilepsy surgery outcome of 17 temporal lobe surgeries were (53%) and (47%) seizure-free, respectively. The first- and third-year epilepsy surgery outcomes of 15 extratemporal epilepsy surgeries were (47%) and (33%) seizure-free. Conclusion. The best outcomes are achieved with temporal epilepsy surgery, mesial temporal sclerosis, and benign CNS tumor. The worst outcomes are from multilobar surgery, dual pathology, and normal MRI.
dc.description.versionPeer Reviewed
dc.identifier.citationAbdulaziz Alsemari, Faisal Al-Otaibi, Salah Baz, et al., “Epilepsy Surgery Series: A Study of 502 Consecutive Patients from a Developing Country,” Epilepsy Research and Treatment, vol. 2014, Article ID 286801, 8 pages, 2014. doi:10.1155/2014/286801
dc.identifier.doihttps://doi.org/10.1155/2014/286801
dc.identifier.urihttp://hdl.handle.net/1880/108250
dc.identifier.urihttps://doi.org/10.11575/PRISM/45693
dc.language.rfc3066en
dc.rights.holderCopyright © 2014 Abdulaziz Alsemari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.titleEpilepsy Surgery Series: A Study of 502 Consecutive Patients from a Developing Country
dc.typeJournal Article
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