Seroprevalence of Cytomegalovirus, Toxoplasma gondii, Syphilis, and Hepatitis B and C Virus Infections in a Regional Population Seropositive for HIV Infection
| dc.contributor.author | Johns, Daniel G | |
| dc.contributor.author | Gill, M John | |
| dc.date.accessioned | 2018-09-27T12:28:58Z | |
| dc.date.available | 2018-09-27T12:28:58Z | |
| dc.date.issued | 1998-01-01 | |
| dc.date.updated | 2018-09-27T12:28:58Z | |
| dc.description.abstract | OBJECTIVE: To determine the prevalence of exposure to cytomegalovirus (CMV), Toxoplasma gondii, syphilis, hepatitis B virus (HBV) and hepatitis C virus (HCV) in a large, well characterized, regional population presenting for human immunodeficency virus (HIV) care.DESIGN: Demographic and serological data compiled prospectively in a relational database used for routine patient care. Results were analyzed for statistically significant trends within demographic subpopulations known to be at risk of such infections.PATIENTS AND SETTING: A total of 1274 persons with documented HIV infection in southern Alberta have sought medical care since 1985. Serological status to CMV, T gondii, syphilis, HBV and HCV infections were routinely requested as part of the initial assessment. All patients with serological results available were included in the analysis.RESULTS: CMV infection was found in 84.1% of patients. A lower prevalence of CMV infection in those under 30 yeasr old (Pud_less_than0.001), intravenous drug users (IVDUs) (P=0.001) and in patients with transfusion-acquired HIV (Pud_less_than0.001) was seen. T gondii seropositivity was found in 10.6% of patients, with an increased risk of seropositivity in those born outside of Canada (Pud_less_than0.001). Syphilis seropositivity was present in 5.1% of patients, with a higher prevalence in gay males (P=0.1). HBV carrier status was noted in 8.0% of patients, with males having an increased risk (P=0.025). Since 1990, there has been a 17.6% prevalence of HCV, predominantly in IVDUs (Pud_less_than0.001).CONCLUSION: Seroprevalence to common pathogens in HIV disease varies significantly among subpopulations, necessitating individual testing. | |
| dc.description.version | Peer Reviewed | |
| dc.identifier.citation | Daniel G Johns and M John Gill, “Seroprevalence of Cytomegalovirus, Toxoplasma gondii, Syphilis, and Hepatitis B and C Virus Infections in a Regional Population Seropositive for HIV Infection,” Canadian Journal of Infectious Diseases, vol. 9, no. 4, pp. 209-214, 1998. doi:10.1155/1998/380687 | |
| dc.identifier.doi | https://doi.org/10.1155/1998/380687 | |
| dc.identifier.uri | http://hdl.handle.net/1880/108636 | |
| dc.language.rfc3066 | en | |
| dc.rights.holder | Copyright © 1998 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |
| dc.title | Seroprevalence of Cytomegalovirus, Toxoplasma gondii, Syphilis, and Hepatitis B and C Virus Infections in a Regional Population Seropositive for HIV Infection | |
| dc.type | Journal Article |