Prevalence, Risk Factors and Short Term Outcomes of Hypophosphatemia among Very Low Birth Weight Infants: An Exploratory Pilot Study

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atmire.migration.oldid5335
dc.contributor.advisorFenton, Tanis
dc.contributor.advisorSauve, Reg
dc.contributor.authorAl-Wassia, Haydi
dc.contributor.committeememberLyon, Andrew
dc.contributor.committeememberRose, Sarah
dc.date.accessioned2017-01-30T23:07:42Z
dc.date.available2017-01-30T23:07:42Z
dc.date.issued2017
dc.date.submitted2017en
dc.description.abstractBackground: Health care professionals face challenges in improving survival rates among very low birth infants who are at risk of hypophosphatemia. We aimed to identify the prevalence and predictive factors of hypophosphatemia. Methods: Prospective, exploratory pilot study of 106 infants admitted to intensive care unit at Foothills Hospital, Calgary between October 1, 2011 and June 1, 2012. Results: The prevalence of hypophosphatemia was 77%. Hypophosphatemic infants had significantly lower birth weight (p< 0.001) and gestational age (p< 0.001). Furthermore, respiratory distress syndrome (RDS) (p = 0.002), intraventricular hemorrhage (IVH) ≥ grade III (p =0.020), and hyperglycemia (p = 0.013) were more frequent among hypophosphatemic infants. Birth weight modified the association between RDS, IVH, hyperglycemia and hypophosphatemia. Conclusion: Hypophosphatemia is common in premature infants. Further research should determine whether premature birth and the associated metabolic consequences as well as the severity of the accompanying comorbidities increase the risk of hypophosphatemia.en_US
dc.identifier.citationAl-Wassia, H. (2017). Prevalence, Risk Factors and Short Term Outcomes of Hypophosphatemia among Very Low Birth Weight Infants: An Exploratory Pilot Study (Master's thesis, University of Calgary, Calgary, Canada). Retrieved from https://prism.ucalgary.ca. doi:10.11575/PRISM/27425en_US
dc.identifier.doihttp://dx.doi.org/10.11575/PRISM/27425
dc.identifier.urihttp://hdl.handle.net/11023/3604
dc.language.isoeng
dc.publisher.facultyGraduate Studies
dc.publisher.institutionUniversity of Calgaryen
dc.publisher.placeCalgaryen
dc.rightsUniversity of Calgary graduate students retain copyright ownership and moral rights for their thesis. You may use this material in any way that is permitted by the Copyright Act or through licensing that has been assigned to the document. For uses that are not allowable under copyright legislation or licensing, you are required to seek permission.
dc.subjectMedicine and Surgery
dc.subject.otherVery low birth weight
dc.subject.otherprevalence
dc.subject.otherrisk factors
dc.subject.otherhypophosphatemia
dc.titlePrevalence, Risk Factors and Short Term Outcomes of Hypophosphatemia among Very Low Birth Weight Infants: An Exploratory Pilot Study
dc.typemaster thesis
thesis.degree.disciplineCommunity Health Sciences
thesis.degree.grantorUniversity of Calgary
thesis.degree.nameMaster of Science (MSc)
ucalgary.item.requestcopytrue
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