A Case of Dilated Cardiomyopathy Associated with 3-Hydroxy-3-Methylglutaryl-Coenzyme A (HMG CoA) Lyase Deficiency
Date
2009-11-04
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
3-hydroxy-3-methylglutaryl-coenzyme A (HMG CoA) lyase deficiency is an inborn error of metabolism characterized by impairment of ketogenesis and leucine catabolism resulting in an organic acidopathy. In 1994, a case of dilated cardiomyopathy and fatal arrhythmia was reported in a 7-month-old infant. We report a case of dilated cardiomyopathy in association with HMG CoA lyase deficiency in a 23-year-old man with the acute presentation of heart failure. To our knowledge, this is the first case reported in an adult.
Description
Keywords
Citation
Alexander A. C. Leung, Alicia K. Chan, Justin A. Ezekowitz, and Alexander K. C. Leung, “A Case of Dilated Cardiomyopathy Associated with 3-Hydroxy-3-Methylglutaryl-Coenzyme A (HMG CoA) Lyase Deficiency,” Case Reports in Medicine, vol. 2009, Article ID 183125, 3 pages, 2009. doi:10.1155/2009/183125